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By Atlas High Purity Solutions team • February 2, 2016

Ultrapure Water Loop Upgrade for New England Biotech Manufacturer

Atlas High Purity Solutions summarizes an ultrapure water loop upgrade project completed for a BioTech Manufacturing facility in New England.


Challenge: A premier biotech manufacturing facility was experiencing higher than normal bacteria counts (as measured by CFU/ml). The problem was heightened during the summer months when temperatures in its ultrapure water loop distribution frequently escalated. It became apparent that loop velocity was inadequate and the existing UV was under-sized for the loop flow rate.

Solution: Atlas and Pure Flow sized pumps to maintain proper velocity of reverse osmosis (RO) water through the 2” line. Grundfos CRNE series pumps were selected, which included integrated VFDs. An over-sized Aquafine CSL series 254nm UV was selected for continuous disinfection. New exchange deionization (DI) tanks loaded with ResinTech MBD 15 LTOC were added to accommodate for the increased flow. Finally, absolute sub-micron final filtration was added for post treatment after the DI tanks. The increased velocity and UV dosage have resolved the bacteria issues and the end user is satisfied with the solution.  


Ultrapure water loop upgrade


Atlas High Purity Solutions has been designing, installing, and servicing high purity water systems for more than thirty years, and is the leading provider in the northeast United States.

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